Pityriasis rubra pilaris successfully treated with infliximab.

Sir, Pityriasis rubra pilaris (PRP) is an uncommon, idiopathic, papulosquamous disorder that often progresses to erythroderma and causes disabling keratoderma. The disease is classified into 5 groups on the basis of clinical appearance, behaviour and prognosis, as proposed by Griffiths in 1980 (1). Recently, a sixth group has been proposed in order to acknowledge the HIV-associated type of PRP (2). No single therapy is universally effective, and some cases are resistant to multiple therapies. We describe here a case of recalcitrant type I, adult-onset PRP that was treated successfully with infliximab.